BIOINFORMATICS SEMINAR SERIES: Fall 2011
STATISTICAL BIOINFORMATICS SEMINAR SERIES
STAT 598B is a 1 credit seminar course (public is welcome)
4:30pm on Tuesdays in HORT 117

Past Seminars (scroll down for current)
FALL SPRING
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  • Spring 2011 seminar series speakers
  • FALL 2011 Schedule:

    Tuesday, August 23, 2011, 4:30pm, HORT 117
    RW Doerge, Department of Statistics and Department of Agronomy, Purdue University
    This is an organizational meeting. All registered students must attend. If you need a registration form signed, please bring it to class.

    Tuesday, August 30, 2011, 4:30pm, HORT 117
    Rebecca Doerge , Department of Statistics, Purdue University
    "Part 1: Beginning a Job Search: Academic, Industry, Government..."

    Associated reading:
    1. Center for Career Opportunities (CCO), Purdue University

    2. Applying for a Job (U.S. Department of Labor)

    3a. How to write a cover letter.
    3b. How to write an academic cover letter.

    4. Academic Job Application Checklist

    5. Academic Job Interview Advice

    6. Academic Interview Questions

    7. Tricky (Industry) Interview Questions

    Tuesday, September 6, 2011, 4:30pm, HORT 117
    NO SEMINAR.

    Tuesday, September 13, 2011, 4:30pm, HORT 117
    Hongmei Jiang, Department of Statistics, Northwestern University
    "Statistical and Computational Challenges for Metagenomics Analysis Based on Next-Generation Sequencing Data"

    Associated reading:
    Daniel H. Huson, Alexander F. Auch, Ji Qi, and Stephan C. Schuster. 2007. MEGAN analysis of metagenomic data.Genome Research.

    Tuesday, September 20, 2011, 4:30pm, HORT 117
    Rebecca Doerge, Department of Statistics, Purdue University
    "The job interview and what to do when you get an offer (academic, industry, etc.)"

    Associated reading:
    1. Center for Career Opportunities (CCO), Purdue University

    Tuesday, September 27, 2011, 4:30pm, HORT 117
    Daniela Witten, Department of Biostatistics, University of Washington, Seattle, WA
    "Sparse method for unsupervised learning in high dimensions, with applications to omics data"

    Associated reading:
    1. Witten DM and R Tibshirani (2010) A framework for feature selection in clustering. Journal of the American Statistical Association 105(490): 713-726.

    2. Friedman J, Hastie T, and R Tibshirani (2007) Sparse inverse covariance estimation with the graphical lasso. Biostatistics 9: 432-441.

    Tuesday, October 4, 2011, 4:30pm, HORT 117
    Theodore Alexandrov, Center for Industrial Mathematics (ZeTeM), University of Bremen
    "MALDI imaging mass spectrometry: statistical data analysis and current computational challenges"

    Associated reading:
    1. J. Watrous, T. Alexandrov, P. Dorrestein (2011) The evolving field of imaging mass spectrometry and its impact on future biological research. Journal of Mass Spectrometry, 46(2):209-222

    2. T. Alexandrov, M. Becker, S.-O. Deininger, G. Ernst, L. Wehder, M. Grasmair, F. von Eggeling, H. Thiele, P. Maass (2010) Spatial segmentation of imaging mass spectrometry data with edge-preserving image denoising and clustering. Journal of Proteome Research, 9(12), 6535-6546

    Tuesday, October 11, 2011, 4:30pm, HORT 117
    NO SEMINAR. FALL BREAK.

    Tuesday, October 18, 2011, 4:30pm, HORT 117
    Jason Mezey, Department of Biological Statistics and Computational Biology, Cornell University and Department of Genetic Medicine, Weill Cornell Medical College
    "Biological network and disease risk factor discovery by regularized analysis of genome-wide data"

    Associated reading:
    Benjamin A. Logsdoni and Jason Mezey. 2010. Gene Expression Network Reconstruction by Convex Feature Selection when Incorporating Genetic Perturbations. PLoS Computational Biology.

    Tuesday, October 25, 2011, 4:30pm, HORT 117
    Alexey I. Nesvizhskii, Department of Pathology, Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI
    "Label-free quantitative proteomics: methods and applications"

    Associated reading:
    1. H. Choi, D. Fermin, and A.I. Nesvizhskii. 2008. Significance analysis of spectral count data in label-free shotgun proteomics. Mol. Cell. Proteomics 7, 2373-2385.

    2. H. Choi, B. Larsen, Z.Y. Lin, B. Breitkreutz, Z.S. Qin, M. Tyers, A.C. Gingras, A. I. Nesvizhskii. 2011. SAINT: probabilistic scoring of affinity purification-mass spectrometry data. Nature Methods 8: 70-73.

    Tuesday, November 1, 2011, 4:30pm, HORT 117
    Alison Motsinger-Reif, Department of Statistics, North Carolina State University, Raleigh, NC
    "Ex-Vivo Modeling for Heritability Assessment and Genetic Mapping in Pharmacogenomics"

    Associated reading:
    Peters et al. 2011. Pharmacogenomic characterization of US FDA-approved cytotoxic drugs. Pharmacogenomics. 12(10), 1407-1415.

    Tuesday, November 8, 2011, 4:30pm, HORT 117
    No Seminar.

    Tuesday, November 15, 2011, 4:30pm, HORT 117
    Bhramar Mukherjee, Department of Biostatistics, University of Michigan
    "Statistical Methods For Analyzing Gene-Environment Interaction"

    Associated reading:
    1. B. Mukherjee and N. Chatterjee. 2008. Exploiting Gene-Environment Independence for Analysis of Case-Control Studies: An Empirical Bayes-Type Shrinkage Estimator to Trade-Off between Bias and Effciency. Biometrics 64, 685-694.

    2. B. Mukherjee, J. Ahn, S.B. Gruber and N. Chatterjee. Testing Gene-Environment Interaction in Large Scale Case-Control Association Studies: Possible Choices and Comparisons. American Journal of Epidemiology (to appear).

    Tuesday, November 22, 2011, 4:30pm, HORT 117
    No Seminar.

    Tuesday, November 29, 2011, 4:30pm, HORT 117
    John Stevens, Department of Mathematics and Statistics, Utah State University, Logan, UT
    "Gene Set Testing to Characterize Multivariately Differentially Expressed Genes"

    Associated reading:
    1. Nettleton et al. (2008) "Identification of differentially expressed gene categories in microarray studies using nonparametric multivariate analysis." Bioinformatics 24(2):192-201.
    2. Fridley et al. (2010) "Self-contained gene-set analysis of expression data: An evaluation of existing and novel methods." PLoS ONE 5(9):e12693.



    The Bioinformatics Seminar is over for the semester. Thank you and see you Spring 2012!!!


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    Please contact doerge@purdue.edu if there is a speaker (including yourself) you would like to invite for this series, or if you would like to be added to the weekly email list.