Title: "Computational Genomics: Developing Workflow Systems for Data Processing and Management"
Speaker: Shannon Schlueter, Department of Computer and Information Technology, Purdue University
Place: Mechanical Engineering (ME) 161; November 27, 2007, Tuesday, 4:30pm

Abstract

The ever increasing amount of publicly available data resources has created a burden of necessity for researchers. Computational thinking and the development of more sophisticated and domain/context sensitive computational tools is often prerequisite to hypothesis driven research. Proper software design methods and the use of data management frameworks can alleviate this burden. This work studies the development and application of such frameworks in the field of computational genomics. Through integration of high performance and grid computing, grid data storage and availability, sophisticated domain centric tools, and web standards a new era of informatics driven research has emerged. We will discuss how these tools will change both university curriculum in the sciences and how we as researchers will conduct research in the future.

Associated Reading:

Schlueter SD, Wilkerson MD, Dong Q, Brendel V. xGDB: open-source computational infrastructure for the integrated evaluation and analysis of genome features. Genome Biol. 2006;7(11):R111.

Wilkerson MD, Schlueter SD, Brendel V. yrGATE: a web-based gene-structure annotation tool for the identification and dissemination of eukaryotic genes. Genome Biol. 2006;7(7):R58.

Duncan Hull, Katy Wolstencroft, Robert Stevens, Carole Goble, Mathew R. Pocock, Peter Li and Tom Oinn Taverna: a tool for building and running workflows of services Nucleic Acids Research 2006 34(Web Server issue):W729-W732; doi:10.1093/nar/gkl320



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