MBA:
Model-Based Assignment


A software for inferential assignment of protein
backbone nuclear magnetic resonances

 

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Installation

Input files

Execution

Output

Convergence

MBA is a Java program for automated assignment and assessment of uncertainty of protein backbone NMR. It is based on a statistical model for NMR spectra, and employs a tree-based algorithm of stochastic optimization.

The program is open source and is available under the GPL licence as is with no guarantees.

 

References:

O. Vitek, C. Bailey-Kellogg, B. A. Craig, J. Vitek. "Inferential backbone assignment for sparse data." J. Biomolecular NMR 35: 187-208, 2006.

O. Vitek, C. Bailey-Kellogg, B. A. Craig, P. Kuliniewicz, J. Vitek. "Reconsidering complete search algorithms for protein backbone NMR assignment." Bioinformatics, 21: ii230-ii236, 2005.

O. Vitek, J. Vitek, B. A. Craig, C. Bailey-Kellogg. "Model-based assignment and inference of protein backbone nuclear magnetic resonances, Statistical Applications in Genetics and Molecular Biology", 3: Article 6, 2004.

 

Contact:

Olga Vitek