Title: "Development of an Integrated "Omics" Cyberinfrastructure"
Speaker: David E Salt, Bindley Bioscience Center, Purdue University
Place: Mechanical Engineering (ME) 161; Tuesday, 4:30pm


Advances in genomic, ionomic, metabolomic, and proteomic methodologies, based upon mass spectrometry and related molecular-cellular imaging technologies, are driving the escalation and proliferation of massive data sets on biological systems. The process is transforming the laboratory from a single-scientist enterprise into an assembly line that transforms samples (raw material) into knowledge (results and reports). By developing a new computational infrastructure that offers an open, scalable architecture that completes an assembly line process for data generation, reduction, and knowledge generation within an integrated system we hope to improve our ability to capture knowledge from such massive data sets. At the core of this new environment will be a robust instrument-independent data management engine including a unified data capture, repository and reduction system to maintain standardized persistent metadata and integrate critical molecular information with other complex data systems. The Purdue Ionomics Information Management System (PiiMS) is being used to prototype such a systems, which will then be extended for the integration of metabolomic and proteomic discovery platforms.

Co-authors and Collaborators on this work include:

Seza Orcun (2), Shrinivas S Jandhyala (3), Brad Kennedy (3), Brett Lahner (1), Xiang Zhang (1), and Ivan Baxter (1)

(1) Bindley Bioscience Center, Purdue University
(2) e-Enterprise Center, Purdue University
(3) Discovery Park Applications Development, Purdue University

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