Title: "Solving Virus Structures Using Single Particle Cryo-Electron Microscopy"
Speaker: Wen Jiang, Department of Biological Sciences, Purdue University
Place: Mechanical Engineering (ME) 161; Tuesday, 4:30pm


Single particle cryo-electron microscopy (cryo-EM) is an emerging technique to solve structures of macromolecular complexes whose dimensions range roughly from 100 to 1,000(A) in diameter providing information with resolution of 5 to 50(A). This technique fills the gap between X-ray crystallography and optical microscopy. In this presentation, I will first give an overview of cryo-EM technique and then use several virus structures solved by us as examples to illustrate the basics and the significant progresses in cryo-EM technique.

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