Title: "A Physiologist's View of QTL Analysis for Determining GXE Interactions"
Speaker: James Fleet; Department of Nutrition Science, Purdue University

Place: Lilly (LILY) Hall G126
Date: November 4, 2014; Tuesday
Time: 4:30pm


Optimal bone health is known to depend on both genetic and environmental factors. We have used quantitative trait loci (QTL) mapping in recombinant inbred mouse lines to study the interaction between genetics and dietary calcium intake as it affects whole body utilization of calcium and the acquisition of peak bone mass during growth. Challenges we've faced include: selecting a genetic model system, understanding alternative approaches to QTL mapping, and using bioinformatics approaches for candidate gene selection. I'll give an overview of our research and the rationale for decisions we've made to get where we are today. In addition, I'll explain the choices we're making to move our research forward in the future.

Associated reading:
1. TBA

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