Myra Samuels Memorial Lecture

Whole Genome Optical Mapping

Professor Michael S. Waterman
Professor of Biological Sciences, Mathematics, Computer Science
University of Southern California

Start Date and Time: Thu, 13 Apr 2006, 4:30 PM

End Date and Time: Thu, 13 Apr 2006, 5:30 PM

Venue: MATH 175

Refreshments: Following the seminar at 5:30 p.m. in the Mathematical Sciences Library Lounge

Abstract:

An innovative new technology, optical mapping, is used to infer the genome map of the location of short sequence patterns called restriction sites. The technology, developed by David Schwartz, allows the visualization of the maps of randomly located single molecules around a million base pairs in length. The genome map is constructed from overlapping these shorter maps. The mathematical and computational challenges come from modeling the measurement errors and from the process of map assembly.

Professor Waterman is a member of the National Academy of Sciences and the French Academie des Sciences.

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